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ea0081oc13.2 | Oral Communications 13: Adrenal and Cardiovascular Endocrinology 2 | ECE2022

Early post-operative ACTH-stimulated aldosterone predicts long-term biochemical outcome in primary aldosteronism

Bruedgam Denise , Adolf Christian , Schneider Holger , Wegmann Verena , Schwarzlmueller Paul , Mueller Lisa , Holler Finn , Lechner Benjamin , Handgriff Laura , Ladurner Roland , Deniz Sinan , Williams Tracy Ann , Beuschlein Felix , Reincke Martin , Heinrich Daniel

Introduction: Primary aldosteronism (PA) is the most common surgically curable cause for endocrine hypertension. Patients with unilateral aldosterone-producing adenoma undergo adrenalectomy (ADX). Clinical and biochemical outcome is assessed 6-12 months after ADX according to PASO consensus. To reduce unnecessary follow-up visits and change in medication for diagnostic purposes for potentially cured patients after ADX, a prediction tool is needed. Previous research had shown g...

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ea0099p16 | Adrenal and Cardiovascular Endocrinology | ECE2024

False-positive and false-negative results during screening, confirmatory testing and subtyping for suspected primary aldosteronism: lessons from Prosaldo

Constantinescu Andreea Georgiana , Pamporaki Christina , Alessi Francesco , Passauer Jens , Remde Hanna , Kuerzinger Lydia , Fuss CarminaTeresa , Schulze Manuel , Peitzsch Mirko , Horvath Andrea , Yang Jun , Bruedgam Denise , Williams TracyAnn , Reincke Martin , Gruber Sven , Beuschlein Felix , Lenders Jacques , Eisenhofer Graeme

Background: Diagnostic stratification of patients with suspected primary aldosteronism (PA) is a multistep process reliant on tests that are not infallible. Only through prospective studies can diagnostic accuracy be appropriately assessed.Methods: The PROSALDO trial enrolled 819 patients between 2019 and 2023 to assess steroid profiles against routine tests for diagnostic stratification. A combination of these tests and outcome assessments, including me...

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Endocrine Abstracts

Early post-operative ACTH-stimulated aldosterone predicts long-term biochemical outcome in primary aldosteronism

False-positive and false-negative results during screening, confirmatory testing and subtyping for suspected primary aldosteronism: lessons from Prosaldo

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